Organic Chemistry 2

• 1. Benzene and Aromaticity

• 1.1: Naming Aromatic Compounds

  Naming Aromatic Compounds
  1.2: Structure and Stability of Benzene

  Strucutre and Stability of Benzene
  1.3: Aromaticity and Huckel 4n+2 Rule

  Aromaticity and Huckel's Rule Aromatic Molecules Examples
  1.4: Aromatic Ions and Aromatic Heterocycles

  Heteroaromatic Molecules Aromaticity of Charged and Heterocyclic Compounds
  1.5: Additional Text Based Resources

  Naming Aromatic Compounds Benzene Structure and Stability Rules for Aromaticity Huckel's Rule Aromatic ions Aromatic Heterocycles
  1.6: Practice Problems

  Aromatic or Not?

• 2. Electrophilic Aromatic Substitution (EAS)

• 2.1: Introduction to EAS

  Intro to Electrophilic Aromatic Substitution EAS Reactions Overview
  2.2: Alkylation and Acylation of Aromatic Rings

  Friedel Crafts Alkylation and Acylation
  2.3: Substituent Effects in EAS

  EAS Ortho-Para Directors vs EAS Meta Directors
  2.4: Nucleophilic Aromatic Substitution

  Nucleophilic Aromatic Substitution Nucleophilic Aromatic Substitution
  2.5: Oxidation of Aromatic Compounds

  Aromatic Side Chain Oxidation Benzylic Bromination
  2.6: Reduction of Aromatic Compounds

  Oxidation and Reduction of Aromatic Compounds
  2.7: Additional Text-Based Resources

  Electrophilic Aromatic Substitution Substituent Effect in EAS Nucleophilic Aromatic Substitution Oxidation of Aromatic Compounds Reduction of Aromatic Compounds
  2.8: Practise Problems

  Electrophilic Aromatic Substitution

• 3. Conjugated Compounds and Ultraviolet Spectroscopy

• 3.1: Stability of Conjugated Dienes

  Stability of Conjugated Dienes- Molecular Orbital Theory
  3.2: Electrophilic Addition to Conjugated Dienes

  Electrophilic Addition to Conjugated Dienes
  3.3: Kinetic vs Thermodynamic Control of Reactions

  Thermodynamic vs Kinetic Control Kinetic vs Thermodynamic Stability of Dienes
  3.4: Diels-Alder Reaction

  Diels-Alder Reaction- Part 1 Diels-Alder Reaction- Part 2
  3.5: Ultraviolet Spectroscopy

  Ultraviolet Spectroscopy
  3.6: Conjugation

  Color and Conjugation in Organic Compounds
  3.7: Additional Text-Based Resources

  Stability of Conjugated Dienes - MO Theory Electrophilic Addition to Conjugated Dienes Kinetic vs Thermodyanmic Control of a Reaction Diels-Alder Reaction Ultraviolet Spectroscopy Conjugation and Color
  3.8: Practise Problems

  Diels-Alder Practice Problems

• 4. Alcohols and Phenols

• 4.1: Naming Alcohols and Phenols

  How to name alcohols and phenols? Nomenclature of Alcohols Primary, Secondary, and Tertiary Alcohols
  4.2: Properties of Alcohols

  Properties of Alcohols
  4.3: Preparation of Alcohols

  Synthesis of Alcohols Grignard Reagents
  4.4: Reaction of Alcohols/button>

  Substitution Reactions of Alcohols Elimination Reactions of Alcohols
  4.5: Oxidation of Alcohols

  Oxidation of Alcohols
  4.6: Protection of Alcohols

  Protecting Groups for Alcohols
  4.7: Phenols and Their Reactions

  Reactions of Phenols
  4.8: Additional Text-Based Resources

  Naming Alcohols Properties of Alcohols Preparation of Alcohols Reactions of Alcohols Oxidation of Alcohols Protection of Alcohols Phenols and Their Reactions
  4.9: Practise Problems

  Alcohol Reactions Practice Alcohol and Phenols Reactions Practice Problems

• 5. Ether and Epoxides

• 5.1: Nomenclature and Properties of Ethers

  Naming ethers
  5.2: Preparing Ethers

  Synthesis of Ethers
  5.3: Reaction of Ethers

  Reactions of Ethers
  5.4: Epoxides and Their Reactions

  Naming Epoxides Synthesis of Epoxides Ring Opening of Epoxides Reactions of Epoxides
  5.5: Thiols and Sulfides

  Thiols Sulfides
  5.6: Additional Text-Based Resources

  Names and Properties of Ethers Williamson Ether Synthesis Ethers from Alkenes, Tertiary Alkyl Halides, and Alkoxymercuration Epoxides Thiols and Sulfides
  5.7: Practise Problems

  Ethers & Epoxides Practice Problems

• 6. Structure Determination: Mass Spectrometry and Infrared Spectroscopy

• 6.1: Mass Spectrometry

  Introduction to Mass Spectrometry Mass Spectrometry-part 1 Mass Spectrometry- part 2 Mass Spectrometry- part 3 How to Interpret Mass Spectra? IR Spectroscopy and Mass Spectrometry
  6.2: Infrared Spectroscopy

  Introduction to IR Spectroscopy Introduction to IR Spectroscopy IR Spectroscopy IR Spectroscopy IR Spectroscopy Examples
  6.3: Additional Text-Based Resources

  Mass Spectrometry Infrared Spectroscopy
  6.4: Practise Problems

  Mass Spectrometry Practice IR Spectrometry Practice

• 7. Aldehydes and Ketones: Nucleophilic Addition Reactions

• 7.1: Naming Aldehyde and Ketones

  Naming Aldehydes/Ketones & Their Properties Aldehyde and Ketones Overview
  7.2: Preparing Aldehyde and Ketones

  Preparation of Aldehydes and Ketones Overview Synthesis of Aldehydes and Ketones
  7.3: Oxidation of Aldehydes and Ketones

  Oxidation of Aldehydes and Ketones
  7.4: Nucleophilic Addition Reactions of Ketones

  Introduction to Nucleophilic Addition of Aldehydes and Ketones Imine and Enamine Formation Nucleophilic Addition of Carbon Nucleophiles Witting Reaction Formation of Hemiacetals and Acetals Cyclic Acetals as Protecting Group for Alcohols
  7.5: Additional Text-Based Resources

  Naming aldehydes and Ketones Preparing Aldehydes and Ketones Oxidation of Aldehydes and Ketones Aldehydes and Ketones Reactions
  7.6: Practice Problems

  Aldehydes and Ketones- Part 1 Aldehydes and Ketones- Part 2

• 8. Carboxylic Acids and Nitriles

• 8.1: Naming Carboxylic Acids and Acid Derivatives

  Naming Carboxylic Acids and Acid Derivatives Naming Nitriles
  8.2: Structure, Properties, and Acidity of Carboxylic Acids

  Structure and Properties of Carboxylic Acids
  8.3: Preparing Carboxylic Acids

  Properties and Synthesis of Carboxylic Acids Preparation of Carboxylic Acids Reactions
  8.4: Nitriles and Their Reactions

  Nitriles- Reaction Summary Synthesis and Reactions of Nitriles
  8.5: Additional Text-Based Resources

  Naming Carboxylic Acids and Nitriles Properties of Carboxylic Acids Preparation of Carboxylic Acids Reactions of Nitriles
  8.6: Practice Problems

  Carboxylic Acids Practice Problems

• 9. Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions

• 9.1: Naming Carboxylic Acid Derivatives

  Naming Carboxylic Acids and Acids Derivatives Nomenclature of Carboxylic Acid Derivatives
  9.2: Nucleophilic Acyl Substitution Reactions

  Reactivity of Carboxylic Acid Derivatives Nucleophilic Acyl Substitution Overview Nucleophilic Acyl Substitution Mechanisms Nucleophilic Acyl Substitution Reactions Reaction of Acid Halides Reactions of Acid Anhydrides Reaction of Esters Preparation and Reaction of Amides Reaction of Amides
  9.3: Additional Text-Based Resources

  Nomenclature of Carboxylic Acid Derivatives Nucleophilic Acyl Substitution Reactions Overview Reaction of Esters Fischer Esterification Reaction of Anhydrides Reaction of Amides
  9.4: Practice Problems

  Carboxylic Acids and Carboxylic Acid Derivatives Practice Problems

• 10. Carbonyl Alpha-Substitution Reactions

• 10.1: Keto-Enol Tautomerism

  Keto-Enol Tautomerism
  10.2: Alpha Substitution Reactions

  Mechanism of Alpha Substitution Reactions
  10.3: Alpha Halogenation

  Alpha Halogenation Halogenation of Alpha Position
  10.4: Alpha Hydrogen Atoms

  Alpha Hydrogen of Carbonyl Compounds Acidity of the Alpha Hydrogen
  10.5: Reactions of Enolate Ions

  Enols and Enolates Enolate Ion Formation and Stability of Alpha Acidic Hydrogen Enolate Reactions Alpha Alkylation Malonic Ester Synthesis and Acetoacetic Ester Synthesis Malonic Ester Synthesis Mechanism Acetoacetic Ester Synthesis Mechanism
  10.6: Additional Text-Based Resources

  Keto-Enol Tautomerism Carbonyl Alpha-Substitution Reactions Enolates- Formation, Stability, and Simple Reactions

• 11. Carbonyl Condensation Reactions

• 11.1: Aldol Reaction

  Aldol and Claisen Reactions Aldol Reactions Aldol Addition and Condensation Reaction Mechanism
  11.2: Claisen Condensation Reactions

  Claisen Condensation Reactions Claisen Condensation Reaction Mechanism
  11.3: The Michael Reaction

  Michael Reaction Michael Reaction Mechanism
  11.4: Additional Text-Based Resources

  Aldol Addition and Condensation Reactions Claisen Condensation Reaction The Michael Addition Reaction
  11.5: Practice Problems

  Enols, Enolates, & Aldol Reactions Practice Problems Aldol Reactions Practice Problems

• 12. Amine

• 12.1: Naming Amines

  Naming Amines
  12.2: Structure and Property of Amines

  Amines Basicity of Amines
  12.3: Synthesis of Amines

  Synthesis of Amines Retrosynthesis with Amines
  12.4: Reaction of Amines and Aryl Amines

  Hofmann Elimination Sandmeyer Reactions EAS Reactions with Nitrogen Heterocycles
  12.5: Heterocyclic Amines

  Heterocycles: Furan, Thiophene, and Pyrrole Heterocycles: Pyridine
  12.6: Additional Text-Based Resources

  Naming Amines Properties of Amines Synthesis of Amines Reactions of Amines Reactions of Amines Reactions of Aryl Amines Heterocyclic Amines
  12.7: Practice Problems

  Amine Reactions and Syntheses Practice Problems 1 Amine Reactions and Syntheses Practice Problems 2 Amines Review Practice Problems Amines Practice